Get Cancer Drug Design and Discovery PDF

By Stephen Neidle

ISBN-10: 0123694485

ISBN-13: 9780123694485

The last word resource of knowledge at the layout of recent anticancer brokers, emphasising small molecules, this latest paintings covers contemporary awesome successes due to the human genome and melanoma genomics tasks. those advances have supplied details on ambitions fascinated by particular cancers which are resulting in potent drugs for a minimum of a number of the universal sturdy tumours. distinct sections clarify the elemental underlying ideas of melanoma drug improvement and supply a realistic creation to fashionable equipment of drug layout. attractive to a huge viewers, this is often a very good reference for translational researchers attracted to melanoma biology and drugs in addition to scholars in pharmacy, pharmacology, or medicinal and organic chemistry, and clinicians taking oncology concepts.

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L. (2003). Opportunities and challenges in the development of kinase inhibitor therapy for cancer. Genes Dev. 17, 2998–3010. , Berdini, V. et al. (2007). Identification of novel inhibitors of protein kinase B using fragment-based lead discovery. J. Med. Chem. 50, 2293–2296. L. (2004). Stuart Schreiber: biology from a chemist’s perspective. Interview by Joanna Owens. Drug Discov. Today 9, 299–303. L. (2003). Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer 3, 721–732. Shaffer, C. (2007). Next-generation sequencing outpaces expectations.

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Cancer Drug Design and Discovery by Stephen Neidle

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