Get Cancer-Causing Viruses and Their Inhibitors PDF

By Satya Prakash Gupta

ISBN-10: 1306865956

ISBN-13: 9781306865951

ISBN-10: 1466589779

ISBN-13: 9781466589773

ISBN-10: 1466589787

ISBN-13: 9781466589780

''Cancer-causing viruses, also known as oncoviruses, play a key position within the improvement of definite cancers. They give a contribution to genetic adjustments that disrupt the cellphone cycle equipment, interfering with services comparable to phone progress. Cancer-Causing Viruses and Their Inhibitors provides a plethora of analysis from across the world reputed participants who talk about kinds of oncoviruses, their mechanisms of invasion Read more...

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Extra info for Cancer-Causing Viruses and Their Inhibitors

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XMRV is a murine leukemia virus (MLV) that formed through the recombination of the genomes of two parent MLVs known as preXMRV-1 and preXMRV-2 (Cingöz et al. 2012). MLV is a gammaretrovirus, a genus of the Retroviridae family, and has a single-stranded RNA genome that replicates through a DNA intermediate. The name XMRV was given because the discoverers of the virus initially thought that it was a novel potential human pathogen that was related to but distinct from MLVs. XMRV has now been established as a laboratory contaminant.

SV40 in human cancers—An endless tale? Int J Cancer 107: 687–687. 1 INTRODUCTION Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus that was ­identified as a causative agent of human diseases (Gallo 2005; Takatsuki 2005; Matsuoka and Jeang 2007). HTLV-1 induces malignancy of CD4+ CD25+ T-lymphocytes, adult T-cell leukemia (ATL), and several inflammatory diseases, such as HTLV-1-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) and HTLV-1 u­ veitis (HU), in a small fraction of the HTLV-1-infected individuals (Matsuoka and Jeang 2007; Yasunaga and Matsuoka 2011).

3, which shows that initial infection of HTLV-1 is established by cell-tocell transmission of the virus. In carrier state, HTLV-1 increases its progenies by de novo infection and clonal expansion of infected cells. ) A pictorial representation of HTLV-1 infection and its treatment strategies. 30 Cancer-Causing Viruses and Their Inhibitors HTLV-1-associated diseases develop in a part of the carriers. Antiviral therapies targeting viral proteins, such as RT, protease, and IN, might be effective only in early phases of infection.

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Cancer-Causing Viruses and Their Inhibitors by Satya Prakash Gupta

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