By Satya Prakash Gupta
''Cancer-causing viruses, also known as oncoviruses, play a key position within the improvement of definite cancers. They give a contribution to genetic adjustments that disrupt the cellphone cycle equipment, interfering with services comparable to phone progress. Cancer-Causing Viruses and Their Inhibitors provides a plethora of analysis from across the world reputed participants who talk about kinds of oncoviruses, their mechanisms of invasion and progress, and their existence cycles. The booklet starts with an summary of the oncoviruses came upon up to now and features a short description in their constructions, genotypes, replication, and mechanisms of an infection resulting in cancers. It then explores numerous of those viruses intimately, together with: Human T-cell leukemia virus style 1 (HTLV-1), Hepatitis C virus (HCV), Epstein-Barr virus (EBV), Human papilloma virus (HPV), Human herpes virus eight (HHV-8)/Kaposi's sarcoma-associated herpes virus (KSHV), Human immunodeficiency virus (HIV/AIDS), Oncolytic viruses. This e-book is an important reference for these operating in virology, oncology, and biotechnology. The discoveries offered will permit researchers and clinicians to optimize either ancient and present ways to anti-viral therapies''--Provided by means of publisher. Read more...
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Extra info for Cancer-Causing Viruses and Their Inhibitors
XMRV is a murine leukemia virus (MLV) that formed through the recombination of the genomes of two parent MLVs known as preXMRV-1 and preXMRV-2 (Cingöz et al. 2012). MLV is a gammaretrovirus, a genus of the Retroviridae family, and has a single-stranded RNA genome that replicates through a DNA intermediate. The name XMRV was given because the discoverers of the virus initially thought that it was a novel potential human pathogen that was related to but distinct from MLVs. XMRV has now been established as a laboratory contaminant.
SV40 in human cancers—An endless tale? Int J Cancer 107: 687–687. 1 INTRODUCTION Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus that was identified as a causative agent of human diseases (Gallo 2005; Takatsuki 2005; Matsuoka and Jeang 2007). HTLV-1 induces malignancy of CD4+ CD25+ T-lymphocytes, adult T-cell leukemia (ATL), and several inflammatory diseases, such as HTLV-1-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) and HTLV-1 u veitis (HU), in a small fraction of the HTLV-1-infected individuals (Matsuoka and Jeang 2007; Yasunaga and Matsuoka 2011).
3, which shows that initial infection of HTLV-1 is established by cell-tocell transmission of the virus. In carrier state, HTLV-1 increases its progenies by de novo infection and clonal expansion of infected cells. ) A pictorial representation of HTLV-1 infection and its treatment strategies. 30 Cancer-Causing Viruses and Their Inhibitors HTLV-1-associated diseases develop in a part of the carriers. Antiviral therapies targeting viral proteins, such as RT, protease, and IN, might be effective only in early phases of infection.
Cancer-Causing Viruses and Their Inhibitors by Satya Prakash Gupta