By K. J. Zülch M.D. (auth.)
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Additional resources for Brain Tumors: Their Biology and Pathology
I have seen a 72-year-old man with a pineal tumor whose pleomorphism required that it be considered an anaplastic type of pinealoma (Zulch, 1956). 9. ). I am not convinced that the neurinomas are derived from connective tissue as has been claimed by Mallory and Penfield. Peculiar silver-staining fibers can be demonstrated, but these appear to be specific for neurinomas. In my experience these fibers are not the same as ordinary reticulin fibers. I also consider tumors of peripheral nerves to be neurinomas where the abundantly present epiand endoneuria!
The experiments were carried out on rabbits, guinea pigs, rats, and mice. Further particulars may be found in the contributions of Greene (1951 and 1953). The guinea pig and the mouse are particularly suitable for transplantation experiments. It has been possible, moreover, to culture neuroepithelial tumors on chick embryos and to transplant them for eight generations. However, the tumor lost its characteristic architecture in the process and regained it only upon being transplanted backintomice (Cohn andZimmermann,1955).
Obviously had a diffuse oligodendroglioma. The other brother had changes of a sort related to tuberous sclerosis. Hallervorden subsequently reported on another pair of siblings where the brother died of a giant-cell glioblastoma; and all that is known of the sister is that she died of a brain tumor at the age of 42. Bohmig reported briefly on a similar case. In our collection of cases, the brothers B. are particularly noteworthy; both of them died of glioblastomas of the parieto-occipital region.
Brain Tumors: Their Biology and Pathology by K. J. Zülch M.D. (auth.)