By Stanley J. Robboy M.D., Peter F. Bernhardt M.D., Tim Parmley M.D. (auth.), Robert J. Kurman M.D. (eds.)
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Additional info for Blaustein’s Pathology of the Female Genital Tract
If a streak gonad from a patient with MGD is serially sectioned, a rare primordial follicle may be encountered in what otherwise appears to be a fetal-type ovary admixed with testis with well developed seminiferous tubules. 43 If the term true hennaphroditism is restricted to those patients in whom the ovarian and testicular tissue are both apparent grossly, it should be possible to segregate more clearly those individuals in whom the ovarian tissue may be functional. Gonadal tumors occur in less than 3% of affected individuals.
HematolOgiC malignancies have also been reported, including acute leukemia, Hodgkin's disease, malignant lymphoma, and chronic myelogenous leukemia. Turner Syndrome In the classic form, Turner syndrome is a disorder in which sexually immature phenotypic females of short stature have various congenital anomalies and streak gonads. The Stanley J. Robboy et al. 19. The testis in Klinefelter syndrome. Top: The parenchyma of the 2-cm testis is golden yellow to slightly brown. Bottom: Clusters of Leydig cells (L) surround a seminiferous tubule (5).
Thus, in the series of van Niekerk and Retief,62 three-fourths of patients were raised as males and one-fourth as females. Many patients, however, menstruated and a few became pregnant. Phenotypic males may experience monthly hematuria because of menstruation into a persistent urogenital sinus. With an increased awareness of intersex states, the condition is recognized more often in infants because of ambiguous genitalia, usually in the form of a small phallus (enlarged clitoris). Like MGD, the scrotum may be asymmetric, with the larger, more normal-appearing hemiscrotum containing a testis.
Blaustein’s Pathology of the Female Genital Tract by Stanley J. Robboy M.D., Peter F. Bernhardt M.D., Tim Parmley M.D. (auth.), Robert J. Kurman M.D. (eds.)