Get Biology and Management of Multiple Myeloma (Current Clinical PDF

By James R. Berenson

ISBN-10: 0896037061

ISBN-13: 9780896037069

ISBN-10: 159259817X

ISBN-13: 9781592598175

Specialist physicians and scientific researchers summarize and clarify all of the fresh advances within the biology and remedy of bone marrow-based malignancy. at the organic facet, the authors convey the features of the malignant telephone and describe the numerous roles performed by way of oncogenic alterations, chromosomal anomalies, Kaposi's sarcoma herpes virus, and cytokines. New epidemiological findings and prognostic components also are analyzed. at the medical part, the authors offer a complete evaluate of traditional remedy regimens, in addition to a dialogue of more recent experimental methods regarding immunologic focusing on, inhibitors of drug resistance, and antitumor brokers.

Show description

Read or Download Biology and Management of Multiple Myeloma (Current Clinical Oncology) PDF

Similar hematology books

Clinical Cases in Avian and Exotic Animal Hematology and by Terry W. Campbell, Krystan Grant PDF

Medical instances in Avian and unique Animal Hematology and Cytology demonstrates tips on how to use hemic cytology and cytodiagnosis as a part of the overview of an unique animal sufferer, taking the reader via approximately a hundred genuine scientific situations. With a spotlight on cytological interpretation, the hands-on, functional process allows studying, educating, and comprehension.

Craig S. Kitchens, MD, MACP, Barbara M. Alving, MD, MACP,'s Consultative Hemostasis and Thrombosis PDF

Successfully and successfully diagnose and deal with latest complete variety of clotting and bleeding issues utilizing medical case stories that exhibit real-world difficulties and ideas! for every situation tested, you are going to assessment concise descriptions of its linked indicators, in addition to laboratory findings, prognosis, differential prognosis, and therapy - the entire medical counsel you wish - at your fingertips.

Download PDF by Marcus Hentrich, Stefan K. Barta: HIV-associated Hematological Malignancies

This e-book provides a common creation to and assessment of HIV-associated hematological malignancies, with a unique specialize in functional administration concerns. all of the appropriate malignancies is addressed separately, with an summary of remedy techniques, evaluate of proof relating to their efficacy, and dialogue of healing controversies.

Download PDF by Deborah A. Sesok-Pizzini: Neonatal Transfusion Practices

This publication presents a concise but finished evaluation of neonatal transfusion medication. The textual content covers significant parts of the sphere, together with chapters devoted to pre transfusion trying out, production, criteria and garage; blood product management; particular congenital and purchased problems within the neonate; hemolytic ailment of the infant; intrauterine transfusions; opposed reactions; and ECMO.

Additional info for Biology and Management of Multiple Myeloma (Current Clinical Oncology)

Example text

Friedman GD. Multiple myeloma: relation to propoxyphene and other drugs, radiation and occupation. Int J Epidemiol 1986; 15:423–425. 41. Pottern LM, Heineman EF, Olsen JH, Raffn E, Blair A. Multiple myeloma among Danish women: employment history and workplace exposure. Cancer Causes Control 1992; 3:427–432. 42. Heineman EF, Olsen JH, Pottern LM, Gomez M, Raffn E, Blair A. Occupational risk factors for multiple myeloma among Danish men. Cancer Causes Control 1992; 3:555–568. Chapter 2 / Epidemiology of MM and Related Disease 33 43.

51. Eriksson M, Karisson M. Occupational and other environmental factors and multiple myeloma: a population-based case-control study. Br J Ind Med 1992; 49:95–103. 52. Hansen ES. A follow-up study on the mortality of truck drivers. Am J Ind Med 1993; 23:811–821. 53. Kawachi I, Pearce N, Fraser J. A New Zealand cancer registry-based study of cancer in wood workers. Cancer 1989; 64:2609–2613. 54. Linet MS, McLaughlin JK, Hsing AW, et al. Is cigarette smoking a risk factor for nonHodgkin’s lymphoma or multiple myeloma?

Furthermore, the immunoglobulin gene locus appears responsible for a significant proportion of the translocations that occur within the myeloma cell. The characterization of these translocations has led to the identification of a number of potential oncogenes that may play a major role in the disease development. Thus, a clear understanding of normal immunoglobulin gene rearrangement is needed to understand myeloma pathophysiology. 2. NORMAL IMMUNOGLOBULIN GENE REARRANGEMENT Antibodies are proteins that bind to cellular, bacterial, or viral antigens and, thus, signal their need for removal by the immune system.

Download PDF sample

Biology and Management of Multiple Myeloma (Current Clinical Oncology) by James R. Berenson


by Mark
4.4

Rated 4.43 of 5 – based on 46 votes