Download e-book for kindle: Basics of blood management by Petra Seeber

By Petra Seeber

ISBN-10: 0470670703

ISBN-13: 9780470670705

ISBN-10: 1118338103

ISBN-13: 9781118338100

ISBN-10: 1280778571

ISBN-13: 9781280778575

To lessen transfusion-related morbidity and mortality, it is suggested that an built-in method of blood administration is hired utilizing all to be had instruments to minimize a patient's publicity to donor blood. assembly the necessity for a publication masking the techniques of blood administration as a development in the direction of multidisciplinary blood administration, this re-creation is a crucial source, delivering healthcare execs with a device to increase historical past wisdom in blood administration, its association, tools and instruments. training clinicians may be absolutely ready to effectively commence and run blood administration courses.

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Anabolic steroids The average hematocrit of men is higher than that of women. This is the result of the androgen testosterone stimulating formation of EPO. It increases endogenous EPO production and enhances the sensitivity of eryth- Anemia Therapy I: Erythropoiesis-Stimulating Agents roid progenitors to available EPO. Persons with bilateral nephrectomy do not benefit much from androgen therapy, since the presence of at least one kidney is needed for a favorable response to androgen therapy in anemia.

However, hematide, an EPO-receptor agonist without structural similarity to naturally occurring EPO, may normalize erythropoiesis in PRCA. Another approach to the therapy of PRCA is a short-term regimen of immunosuppressive therapy with corticoids, cyclosporine, cyclophosphamide, immunoglobulins, or plasmapheresis. Spontaneous reversal of the PRCA can occur, but is extremely rare. While rHuEPO mainly influences the erythroid precursors, it has also some influence on megakaryocytes and on precursors of leukocytes.

Wolchok JD, Klimek VM, Williams L, Chapman PB. Prophylactic recombinant epoetin alfa markedly reduces the need for blood transfusion in patients with metastatic melanoma 34 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. Chapter 3 treated with biochemotherapy. Cytokines Cell Mol Ther 1999;5:205–206. Colomina MJ, Bagó J, Pellisé F, Godet C, Villanueva C. Preoperative erythropoietin in spine surgery. Eur Spine J 2004;13 (Suppl 1):S40–S49. Christodoulakis M, Tsiftsis DD. Preoperative epoetin alfa in colorectal surgery: a randomized, controlled study.

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Basics of blood management by Petra Seeber

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