By Stephen M. Bonsib (auth.)
The kidney is an organ with advanced organogenesis prone to a number of misadventures in improvement and is uncovered to a various array of insults of hematogenous and decrease urinary tract beginning. This Atlas of clinical Renal Pathology offers an summary of the advance, macroscopic and microscopic beneficial properties of the conventional kidney. this can be by means of a entire survey of developmental and cystic kidney illnesses, vascular ailments and tubulointerstitial ailments. An emphasis is put on gross diagnostic findings with specific histological correlates. furthermore, the histological, immunofluorescent, immunohistochemical and ultrastructural gains of the key glomerular illnesses and renal transplantation pathology are provided. This compendium of non-neoplastic kidney illnesses illustrates the overwhelming majority ailments you will definitely come upon in surgical and post-mortem pathology.
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Extra info for Atlas of Medical Renal Pathology
31 ARPKD, neonatal onset. Shown is a term infant with ARPKD. Notice the massive abdominal distension from the enormously enlarged kidneys. The thoracic space is very small because the massive kidneys impeded lung development. Thus, this infant died from respiratory failure due to pulmonary hypoplasia Fig. 34 ARPKD, neonatal onset. This is another example of a neonate with severe ARPKD. The diffuse and uniform character of the cysts is apparent and imparts a spongy appearance, thus the term sponge kidney.
Notice the massive abdominal distension from the enormously enlarged kidneys. The thoracic space is very small because the massive kidneys impeded lung development. Thus, this infant died from respiratory failure due to pulmonary hypoplasia Fig. 34 ARPKD, neonatal onset. This is another example of a neonate with severe ARPKD. The diffuse and uniform character of the cysts is apparent and imparts a spongy appearance, thus the term sponge kidney. However, it should not be confused with medullary sponge kidney, a completely different disorder Fig.
The kidneys were not grossly enlarged but contained a few small cysts. Most of the renal parenchyma was completely normal. In this section, two large cysts are present, likely arising in a single nephron Fig. 53 ADPKD. This case of ADPKD shows multiple papillary RCCs. The risk, if any, of RCC in ADPKD is controversial. Most cases reported have been single case reports or small series. No large population-based studies have been performed 38 Fig. 55 ADPKD. This autopsy kidney from another young adult with a family history of ADPKD shows the early stages of disease.
Atlas of Medical Renal Pathology by Stephen M. Bonsib (auth.)