Download e-book for iPad: Atlas of Liver Pathology by Anthony W. H. Chan, Alberto Quaglia, Beate Haugk, Alastair

By Anthony W. H. Chan, Alberto Quaglia, Beate Haugk, Alastair Burt

ISBN-10: 1461491134

ISBN-13: 9781461491132

The liver is a fancy organ because of its exact microscopic constitution, tricky metabolic features and susceptibility to a wide selection of insults, manifesting in numerous histological  patterns.  Atlas of Liver Pathology considers either adjustments noticeable in clinical liver biopsies in addition to lesional biopsies while the specimen has been taken from a mass. The booklet starts off by way of reviewing general constitution and its editions and the optimum techniques for the coaching of histological sections for diagnostic liver pathology. the subsequent chapters are devoted to developmental, metabolic, infectious, drug similar, autoimmune, biliary, vascular and neoplastic problems. sections on liver pathology in being pregnant and transplantation finish the paintings. Macroscopic illustrations are integrated the place applicable. All photos are complemented by way of legends describing the image and offering suitable comparable information.

Authored via nationally and across the world famous pathologists, Atlas of Liver Pathology is a necessary source that serves as a short reference advisor for the prognosis of traditional and weird diseases.

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Example text

Polysplenia, preduodenal portal vein, gut malrotation, congenital heart disease, and laterality and situs anomalies of internal organs). Abdominal ultrasound, hepatobiliary iminodiacetic acid (HIDA) scan, and cholangiogram are important radiologic diagnostic tools. 4 Fig. 28 Biliary atresia. This excised atretic porta hepatis contains multiple small duct remnants. The pathologic features of biliary atresia are influenced by the timing and location of specimens obtained. More than 90% of cases are the result of obliteration of the common hepatic duct at the porta hepatis.

A mitotic figure (centre) is present in a dividing hepatocyte in response to acute hepatitis. Replication of hepatocytes through mitotic division is a key part of regenerative responses in liver and is evident in mild to moderate cellular loss. Of course, mitotic activity also may be prominent in hepatocellular neoplasms. However, atypical mitotic figures are never encountered in regeneration. Fig. 59 Ploidy. Regenerating hepatocytes may show binucleation, vesicular chromatin, and prominent nucleoli.

There are many ballooned hepatocytes, which are characterized by cellular swelling, rarefaction of the cytoplasm, and clumped strands of intermediate filaments. The mimickers of ballooning degeneration are feathery degeneration, steatosis (particularly the microvesicular form), and glycogen-rich hepatocytes. Feathery degeneration is almost indistinguishable from ballooning degeneration, but one can differentiate between them by the presence of cholestasis and/or cholate stasis, frequently associated with feathery degeneration.

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Atlas of Liver Pathology by Anthony W. H. Chan, Alberto Quaglia, Beate Haugk, Alastair Burt


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