By J. Yuan
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90. Von Euler US and Liljestrand G. Observations on the pulmonary arterial blood pressure in the cat. Acta Physiol. Scand. 1946; 12: 301-320. 91. Yaghi A, Paterson NAM, and McCormack G. Nitric oxide does not mediate the attenuated pulmonary vascular reactivity of chronic pneumonia. Am. J. Physiol. 1993; 265: H943-H948. 92. Yamaguchi K, Suzuki K, Naoki K, Nishio K, Sato N, Takeshita K, Kudo H, Aoki T, Suzuki Y, Miyata A, and Tsumura H. Response of intra-acinar pulmonary microvessels to hypoxia, hypercapnic acidosis, and isocapnic acidosis.
Physiol. 2000; 279: H1526-H1533. The editor notes with sadness the passing of Dr. Christopher Dawson, an extraordinary mentor for young investigators and an eminent scientist in the field of pulmonary physiology, and was very grateful that this book contains one of his last works on the heterogeneity of hypoxic pulmonary vasoconstriction. His presence in the scientific community will be sorely missed. 33 Christopher A. , Professor and eminent research scientist died suddenly and unexpectedly on July 12, 2003 at his office.
Thus, the search for a 18 humoral mediator that carries the message from sensor cells to contracting cells has been essentially abandoned. The observation that alveolar hypoxia is so much more an effective stimulus than pulmonary arterial hypoxia has been a major reason that the humoral mediator concept has been difficult to give up. The fact that pulmonary arterial (mixed venous) blood is always hypoxic compared to alveolar gas is the reason that HPV has the potential for matching perfusion to ventilation in the first place.
Arrhythmias and sudden death in athletes by J. Yuan