By Manfred Zierhut, Hans-Georg Rammensee, Wayne Streilein
Lately the significance of antigen-presenting cells and their effect at the eyes has been elucidated. we've realized that just about each constitution of the attention harbors those cells, but they range of their actions and hence within the ways that they guard opposed to - or perform - illnesses of the attention. Antigen-Presenting Cells and the attention summarizes present wisdom approximately ACPs ordinarily, and their position within the eye, specifically.
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Extra info for Antigen-presenting cells and the eye
2microglobulin deficient mice (lack Class I) are incapable of responding to AC inoculation of antigen with ACAID since both classical Class I and Class I-like CD1d are missing. The ACAID inducing APCs are further distinguished by their expression of F4/80 protein. F4/80 protein is a molecule that has long been associated as a marker of tissue macrophages. The F4/80 molecule was identified over twenty years ago as a 160-kDa molecule expressed on the plasma membrane of restricted subsets of mouse macrophages, monocytes, and dendritic cells found throughout the lymphoid system and elsewhere in the body (36).
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Antigen-presenting cells and the eye by Manfred Zierhut, Hans-Georg Rammensee, Wayne Streilein