Download e-book for kindle: Adequate HLA Matching in Keratoplasty (Developments in by R. Sundmacher, F. Bandello

By R. Sundmacher, F. Bandello

ISBN-10: 3805574878

ISBN-13: 9783805574877

‘Immunologic privilege’ of the cornea and anterior chamber has, normally, been believed to be a enough warrantly for survival of the donor cornea. If this failed, it used to be proposal that adjunctive immunomodulating brokers might compensate. however the query of ways to deal with higher tolerance and more secure long term survival of corneal grafts after withdrawal of a powerful immunomodulating protect nonetheless remained unanswered. the answer's human leukocyte antigens (HLA) matching. during this quantity, immunological and medical points are mentioned via popular scientific and experimental immunologists in addition to skilled keratoplasty surgeons. those specialists finish that HLA matching is, actually, a precious adjunct for long term survival of corneal grafts not just in these at excessive probability yet particularly additionally in sufferers at basic hazard. This quantity opens new pathways in the direction of the winning program of HLA matching to keratoplasty surgeons, experimental and scientific immunologists and cornea financial institution officials, while appearing as an relief to ophthalmologists whilst discovering the root to thoroughly recommend their keratoplasty sufferers.

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Extra resources for Adequate HLA Matching in Keratoplasty (Developments in Ophthalmology, 36)

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Transplantation 1986;41:508–514. Claas FHJ, Roelen DL, D’Amaro J, Völker-Dieben HJ: The role of HLA in corneal transplantation; in Immunology of Corneal Transplantation. Buren/NL, Aeolus Press, 1994, p 47. Allansmith MR, Fine M, Payne R: Histocompatibility typing and corneal transplantation. Trans Am Acad Ophthalmol Otol 1974;78:445. Ducrey NM, Glauser MP, Frei PC: Corneal transplantation: ABO blood groups and HLA compatibility. Ann Ophthalmol 1980(July):880. Histocompatibility and Corneal Transplantation 39 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 The Collaborative Corneal Transplantation Studies (CCTS) Research Group: Effectiveness of histocompatibility matching in high-risk corneal transplantation.

Amsterdam, Associated Scientific Publishers, 1973, p 307. Sanfilippo F, MacQueen JM, Vaughn WK, Foulks GN: Reduced graft rejection with good HLA-A and -B matching in high-risk corneal transplantation. N Engl J Med 1986;315:29. Völker-Dieben HJ, D’Amaro J, Kok-van Alphen CC: Hierarchy of prognostic factors for corneal allograft survival. Aust NZ J Ophthalmol 1987;15:11. Völker-Dieben HJ, D’Amaro J: Corneal transplantation: A single-center experience 1976–1988; in Terasaki P (ed): Clinical Transplants 1988.

Irschick E, Miller K, Berger M: Studies on the mechanism of tolerance induced by short-term immunosuppression with cyclosporine in high-risk corneal allograft recipients. I. Analysis of CTL precursor frequencies. Transplantation 1989;48:986–992. Rowden G: The Langerhans cell. Crit Rev Immunol 1981;2:95–180. Pepose JS, Gardner KM, Nestor MS, Foos RY, Pettit TH: Detection of HLA class I and II antigens in rejected human corneal allografts. Ophthalmology 1985;92:1480–1484. Ardjomand N, Komericki P, Radner H, Algner R, Reich ME: Corneal Langerhans cells.

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Adequate HLA Matching in Keratoplasty (Developments in Ophthalmology, 36) by R. Sundmacher, F. Bandello


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